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Tadalafil works by preventing the action of a chemical in your body, called phosphodiesterase type 5. This helps to relax (widen) blood vessels and improves the flow of blood to the penis following sexual stimulation. how does cialis tadalafil work How does Cialis work? Cialis is a phosphodiesterase type 5 (PDE5) inhibitor. Cialis, a brand-name version of tadalafil, is available by prescription in tablet form in four strengths: 2.5 mg; 5 mg; Tadalafil (Cialis) is used to treat erectile dysfunction (ED, impotence; inability to get or keep an erection), and the symptoms of benign prostatic hyperplasia (BPH; an enlarged prostate) which include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency in adult men.
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